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# Quick check: mitosis, fertilisation and sex-linked traits

Year 10 Biology · Genetics

<!-- Speaker note: A self-test on mitosis, how fertilisation and meiosis give variation, and sex-linked inheritance (AC9S10U01, nodes 2, 5 and 6, taught in class; node 6 a hinge). About 16 minutes (Node 2 4 min · Node 5 6 min · Node 6 6 min). -->

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## Today

**We are learning to** a few quick questions on mitosis, how fertilisation and meiosis give variation among siblings, and sex-linked inheritance. Taught in class; use this to check yourself.

- I can say what mitosis produces and why.
- I can explain why siblings differ.
- I can predict an X-linked trait with a Punnett square.

<!-- Speaker note: Before class: A Quick check: a few questions on what students should know for AC9S10U01 nodes 2, 5 and 6, which you teach in class. It has no board, no clip and no new teaching, and it is optional, so it never holds up course completion. Set the width with `?width=minimum`, `typical` (default) or `wider`. Use it as a self-test after your teaching, a starter, or revision. DNA, meiosis and Punnett squares are on screen (nodes 1, 3 and 4). The notation here is XN for the normal allele and Xn for the condition allele; use whichever your class uses, as long as it is consistent. Teacher: Node 2: sort first, then ask students to draw a cell dividing both ways. Teacher: Node 6: have students draw the Punnett square before they read the options. -->

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## Why it matters

> Siblings share both parents but are not copies of each other. And why do some conditions show up more in boys?

<!-- Speaker note: Your teacher covers these in class. The questions check the basics: what mitosis does, how offspring get their genes, and why sex-linked traits behave differently. -->

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## The outcome

**A body cell with 46 chromosomes divides by mitosis. What does each daughter cell have?**

- 23 chromosomes, different from the parent
- 92 chromosomes
- 46 chromosomes, all different from each other
- 46 chromosomes, genetically identical to the parent cell

* Answer: 46 chromosomes, genetically identical to the parent cell

<!-- Speaker note: Mitosis copies the chromosomes and shares them equally, so each daughter cell is a genetic copy with the full number. -->

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## Mitosis or meiosis?

**Is it mitosis or meiosis?**

Groups: Mitosis · Meiosis

Makes two identical cells · Makes gametes · Used for growth and repair · Halves the chromosome number · Keeps the chromosome number the same

* Answer: Makes two identical cells → Mitosis; Makes gametes → Meiosis; Used for growth and repair → Mitosis; Halves the chromosome number → Meiosis; Keeps the chromosome number the same → Mitosis

<!-- Speaker note:  -->

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## Putting it together

**Each human gamete has 23 chromosomes. How many does a fertilised egg have?**

- 92: two copies from each parent
- 23: the same as a gamete
- 46: one set from each parent
- Any number

* Answer: 46: one set from each parent

<!-- Speaker note: Fertilisation joins two gametes, restoring the full number in the next generation. -->

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## Why siblings differ

**Why can two children of the same parents have different genes?**

- Younger children get more of their genes from the mother
- Siblings always get the same genes
- Meiosis shuffles the genes into different gametes, and which sperm meets which egg is random
- Each child gets an exact blend of both parents

* Answer: Meiosis shuffles the genes into different gametes, and which sperm meets which egg is random

<!-- Speaker note: Each gamete is a different mix, and fertilisation combines two at random, so every child gets a different combination (except identical twins). -->

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## Punnett ratios

**Two parents are both Bb (B dominant). What is the chance of a child with genotype bb?**

- 0
- 3 in 4 (75%)
- 1 in 4 (25%)
- 1 in 2 (50%)

* Answer: 1 in 4 (25%)

<!-- Speaker note: Each parent passes B or b with equal chance, so the four combinations BB, Bb, Bb and bb are equally likely: bb is one of the four. -->

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## From parent to gamete

**A parent has the genotype Bb. What gametes can they make?**

- B and b in a 3 to 1 ratio
- All carry B, because it is dominant
- All carry Bb
- Half carry B and half carry b

* Answer: Half carry B and half carry b

<!-- Speaker note: Meiosis separates the pair, so each gamete gets one allele: B or b, equally likely. -->

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## Sex chromosomes

**Which chromosome pair makes a person female or male?**

- XY is female, XX is male
- Another chromosome pair decides; X and Y don't matter
- XX is female, XY is male
- The mother's chromosomes alone decide

* Answer: XX is female, XY is male

<!-- Speaker note: The Y chromosome carries the gene that starts male development. -->

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## A Punnett square

**A mother is a carrier of an X-linked recessive condition (XN Xn). The father does not have it (XN Y). What fraction of their sons is expected to have the condition?**

- Half
- One quarter
- None
- All

* Answer: Half

<!-- Speaker note: Sons get the father's Y and one of the mother's X chromosomes: half get Xn, so half have the condition. Daughters get XN from the father, so none have it, though half are carriers. -->

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## Why more in males?

**Why are X-linked recessive conditions more common in males?**

- Males have only one X, so a single recessive allele is expressed; females need two
- The Y chromosome carries the condition
- Males have two X chromosomes
- Females never carry the allele

* Answer: Males have only one X, so a single recessive allele is expressed; females need two

<!-- Speaker note: A female can have a normal second X that masks the recessive allele. A male has no second X. -->

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## Daughters

**The same parents (XN Xn and XN Y). What about their daughters?**

- All are carriers
- Half have the condition
- None are expected to have the condition, and half are expected to be carriers
- One quarter have the condition

* Answer: None are expected to have the condition, and half are expected to be carriers

<!-- Speaker note: Daughters get the father's XN and one of the mother's X chromosomes: XN XN or XN Xn. None have it; half carry it. -->

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## Exit ticket

**Why is an X-linked recessive condition more common in males?**

* Males have only one X, so one recessive allele is enough; females need two.

<!-- Speaker note: Students answer on paper or a mini whiteboard before the reveal. Anyone who cannot answer needs the main idea again next lesson. Where this leads: Back in class: family pedigree analysis; a mitosis stages practical or models. -->
